French leaders have admitted that the upcoming vote on the EU constitution is lost (hat tip Instapundit). I've read elsewhere that this will affect the EU and I've also read that it isn't that big of a deal. I'm not knowledgeable enough of EU politics to know which view is correct.
I do think the vote is a significant failure for Chirac. He has proven very resilient as a politician, however. It will be interesting to see how he handles this new failure.